The couple has been married for more than two decades and met on the set of the 1994 film, Blown Away. Whitaker and Nash played each other’s love interest onscreen and soon began dating in real life.
The actors wed in Montego Bay, Jamaica in 1996, the tabloid site reports.
They share two daughters Sonnet, 22, and True, 20, and each has a child from previous relationships.
According to Page Six, Whitaker recently listed the family’s Hollywood Hills estate for $6 million.
The court documents cite irreconcilable differences as the reason for the split.