While critics and political pundits all comment on HBO's "Game Change," its authors (Mark Halperin and John Heilemann) both have their sights set on who will run for President in 2016. On MSNBC's "Morning Joe," co-host Willie Geist asked more specifically about a certain runner-up from 2008, asking, "What are the odds this morning that Hillary Clinton runs for President in 2016?" The answer differs sharply from Clinton's comments, but Heilmann answered, saying, "99.4 [percent chance]. I think very high." Halperin added, "A little lower. I think that if Joe Biden wins re-election [as Vice President] and runs, she's much less likely to run."

The conversation stemmed from the context of a New York Times piece by columnist Maureen Dowd titled "Don't Tread On Us," which argues for Hillary Clinton as a presidential candidate. With such issues as contraception, abortion, women's rights, and minority rights all seemingly on the table, is Hillary the inevitable choice in an era packed with firsts?